'KC Star' Investigation Leads to $1 Billion Hepititis C Settlement
hope for Hepatitis C research
Offers New Rapid Diagnostic to Combat "the hidden epidemic -Co-infection
with HIV/Hepatitis C
Hepatitis C-related liver cancer mortality on the rise: report
patients with hepatitis C (HCV) infections experience a lower response rate
to the peginterferon alfa-2a and ribavirin combination treatment than Caucasian
Hep C activist dies at 48
Group Plc (“phynova” and or the “company”)
Granted First UK Patent for PYN17 A Botanical Drug for the Treatment of Hepatitis
HIV/HCV coinfected patients more prone to end-stage liver disease
Media Statement on NICE Guidance for Treatment of Mild Hepatitis C
UK's NICE backs Roche, Schering-Plough hep C drugs
Inovio Reveals Positive Data From The Combined ChronVac-C DNA Vaccine
And Inovio's MedPulser DNA Delivery System - Update
Japan court awards damages over hepatitis C infections
Clinical Trials, Cohort Studies, and Pilot Studies
plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis
C virus RNA at week 4 of treatment.
results of a randomized trial looking at 24 weeks vs 48 weeks of treatment
with peginterferon alpha-2a (40 kDa) and ribavirin combination therapy in patients
with chronic hepatitis C genotype 1.
Effectiveness of interferon plus ribavirin combination in the treatment of naive patients with hepatitis C virus type 5. A French multicentre retrospective study. Bonny C, et al. Aliment Pharmacol Ther. 2006 Aug 15;24(4):593-600.
Long-term follow-up of previous hepatitis C virus positive nonresponders to interferon monotherapy successfully retreated with combination therapy: are they really cured? Ciancio A, et al. Am J Gastroenterol. 2006 Aug;101(8):1811-6. Epub 2006 Jun 16.
A randomised trial to compare the pharmacokinetic, pharmacodynamic, and antiviral effects of peginterferon alfa-2b and peginterferon alfa-2a in patients with chronic hepatitis C (COMPARE). Silva M, et al. J Hepatol. 2006 Aug;45(2):204-13. Epub 2006 Apr 18.
Mental and physical
symptoms associated with lower social support for patients with hepatitis
of interferon therapy on outcome after surgery for hepatitis C virus-related
Prospective Analysis of the Prognostic Value of Biomarkers (FibroTest) in Patients
with Chronic Hepatitis C.
Outcomes and Treatment of Acute Hepatitis C Virus Infection
in a United States Population.
of Hepatitis C Virus Quasispecies during Ribavirin and Interferon-Alpha-2b
Combination Therapy and Interferon-Alpha-2b Monotherapy.
Cancer incidence in
people with hepatitis B or C infection: a large community-based linkage study.
Cofactors associated with liver disease mortality in an HBsAg-positive Mediterranean
cohort: 20 years of follow-up.
Negative HCV-RNA Status Led to a Good Outcome in Chronic Hepatitis C Patients
with Genotype 1b and Super-High Viral Load.
contributions of hepatitis B virus and hepatitis C virus infections to
cirrhosis and primary liver cancer worldwide.
More advanced hepatic fibrosis in hispanics with chronic hepatitis C infection: role of patient demographics, hepatic necroinflammation, and steatosis. Verma S, et al. Am J Gastroenterol. 2006 Aug;101(8):1817-23. Epub 2006 Jun 22.
Basic and Applied Science, Pre-Clinical Studies
Variations in the Viral NS5B Region in Japanese Patients with Chronic Hepatitis C Virus Genotype 1b Infection. Sugihara K, et al. Intervirology. 2006 Aug 21;49(6):319-326 [Epub ahead of print]
CR5Delta32 mutation does not influence the susceptibility to HCV infection, severity of liver disease and response to therapy in patients with chronic hepatitis C. Goyal A, et al. World J Gastroenterol. 2006 Aug 7;12(29):4721-6
cells support viral replication and gene expression of hepatitis C virus
genotype 4 in vitro.
of genetic polymorphism of low-density lipoprotein receptor with chronic
viral hepatitis C infection in Han Chinese.
Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies. Larrea E, et al. Gut. 2006 Aug;55(8):1188-96. Epub 2005 Aug 24.
Dynamics of interferon-specific gene expression in peripheral blood of interferon alfa-naive patients with genotype 1 chronic hepatitis C infection treated with albumin-interferon alfa. Bain VG, et al. Hepatol Res. 2006 Aug;35(4):256-62. Epub 2006 May 30.
inhibitors binding to hepatitis C virus NS5B polymerase reveal a novel mechanism
Viral and Cellular Determinants of Hepatitis C Virus
Envelope-Heparan Sulfate Interaction.
and predictors of hepatitis C virus treatment in HCV-HIV-coinfected subjects.
of peginterferon alfa-2a (40kDa) plus ribavirin in patients with HIV and
hepatitis C virus co-infection.
steatosis is associated with fibrosis, nucleoside analogue use, and hepatitis
C virus genotype 3 infection in HIV-seropositive patients.
Coinfection Impairs CD28-Mediated Costimulation of Hepatitis C Virus-Specific
Hepatitis C virus eradication followed by HBeAg to anti-HBe seroconversion after pegylated interferon-alpha2b plus ribavirin treatment in a patient with hepatitis B and C coinfection. Rautou PE, et al.
Complementary and Alternative Therapies
The effect of antioxidant supplementation on hepatitis C viral load, transaminases and oxidative status: a randomized trial among chronic hepatitis C virus-infected patients. Groenbaek K, et al. Eur J Gastroenterol Hepatol. 2006 Sep;18(9):985-989.
Hepatitis C - contamination of toothbrushes: myth or reality? Lock G, et al. J Viral Hepat. 2006 Sep;13(9):571-3.
From Trials to a Real Hospital Setting: Effectiveness of Pegylated Interferon-alpha-2b/Ribavirin Combination Therapy for Naive Chronic Hepatitis C Patients. Piai G, et al. Dig Dis Sci. 2006 Aug 22; [Epub ahead of print]
Hepatitis C, metabolic syndrome, and inflammatory markers: Results from the Third National Health and Nutrition Examination Survey [NHANES III]. Shaheen M, et al. Diabetes Res Clin Pract. 2006 Aug 16; [Epub ahead of print]
Case finding for hepatitis C in primary care: a cost utility analysis. Thompson Coon J, Fam Pract. 2006 Aug;23(4):393-406. Epub 2006 Jun 23.
C is the most common, chronic blood-borne
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