Hepatitis C Remains Most Common Chronic Systemic Viral
Infection in United States: Caring Ambassadors Program Urges Caution in
Interpretation of CDC Report
Hepatitis A and Hepatitis B Cases at Lowest Levels Ever
TL Biopharma Says Phase I Study Of Hepatitis C Drug
XTL-6865 Safe At High Doses - Update
GPs Armed with New Hepatitis C Resource [UK]
Roche Driving PROGRESS in Treatment of Hepatitis C
Education another weapon against hepatitis C: Celebrity
carriers, including Pamela Anderson, help raise profile of disease
Exchange programs help prevent AIDS, hepatitis C
New York State Health Commissioner: Time to Stop 'Silent
Hep C crisis threat to jails, outside: Curing prisoners is
costly, but not curing them can be deadly
Tech tools can fight isle hepatitis: A support network
envisions rural clinics that use telemedicine to combat the disease
PEGASYS(R) Gets European Approval for a Shorter Treatment
Duration for Some Genotype 1 and 4 Hepatitis C Patients who Show a Rapid
Response to Therapy
Valeant Pharmaceuticals Initiates Taribavirin Phase 2b
Private Home Tattooing
Hep C Policies Failing as Drug Users Fall Ill [Australia]
Church Holds Program About HIV/AIDS, Hepatitis C
Help For Hep C
Inquiry into Sydney Hep C Outbreak [Australia]
Hep C Testing Beginning on Patients [Canada]
Drinking Takes Excessive Toll on Women with Hepatitis C
Hepatitis C drug on way
According to a BBC report, Imperial College experts have developed a potentially cheaper version of an existing Hepatitis C drug by altering the molecular structure.
75 Percent of College Students Report
Risk Factors for Hepatitis C
New hope for Hepatitis C research
Hepatitis C-related liver cancer mortality on the rise: report
clinical trials, cohort studies, and pilot studies
Accidental exposure to HCV antibody-positive blood in hospital and pre-emptive one-shot interferon alpha-2b treatment. Nukaya H, et al. Hepatol Res. 2007 Mar;37(3):179-85.
Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C. Pestka JM, et al. Proc Natl Acad Sci U S A. 2007 Mar 28; [Epub ahead of print]
Musculoskeletal Complaints and Serum Autoantibodies Associated with Chronic Hepatitis C and Nonalcoholic Fatty Liver Disease. Banks SE, et al. Dig Dis Sci. 2007 Mar 27; [Epub ahead of print]
Interferon alfa (pegylated and non-pegylated) and ribavirin for the treatment of mild chronic hepatitis C: a systematic review and economic evaluation. Shepherd J, et al. Health Technol Assess. 2007 Mar;11(11):1-224.
Excess mortality rates in a cohort of patients infected with the hepatitis C virus: a prospective study. Neal K, Irving WL. Gut. 2007 Mar 7; [Epub ahead of print]
Sustained virological response to interferon-alpha is associated with improved outcome in HCV-related cirrhosis: a retrospective study. Bruno S, et al. Hepatology. 2007 Mar;45(3):579-87.
Subthreshold mania as predictor of depression during interferon treatment in HCV(+) patients without current or lifetime psychiatric disorders. Dell'osso L, et al. J Psychosom Res. 2007 Mar;62(3):349-55.
Long-Term Treatment with the Combination of Amantadine and Ribavirin in Hepatitis C Nonresponders. A Case Series. Riley TR 3rd, Taheri MR. Dig Dis Sci. 2007 Mar 31; [Epub ahead of print]
Hepatic steatosis in genotype 4 chronic hepatitis C is mainly because of metabolic factors. Tsochatzis E, et al. Am J Gastroenterol. 2007 Mar;102(3):634-41.patic steatosis in genotype 4 is mostly associated with metabolic factors, similar to those in genotype 1.
Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2. Kawaguchi T, et al. Am J Gastroenterol. 2007 Mar;102(3):570-6.
Compensated hepatitis C: unenhanced MR imaging correlated with pathologic grading and staging. Mitchell DG, et al. Abdom Imaging. 2007 Mar 27; [Epub ahead of print]
Progression of fibrosis in advanced chronic hepatitis C: Evaluation by morphometric image analysis. Goodman ZD et al. Hepatology. 2007 Mar 28;45(4):886-894
Screening for Hepatocellular Carcinoma Among Veterans With Hepatitis C on Disease Stage, Treatment Received, and Survival. Leykum LK, et al. Clin Gastroenterol Hepatol. 2007 Mar 21; [Epub ahead of print]
Post-load insulin resistance is an independent predictor of hepatic fibrosis in Virus C Chronic Hepatitis and in Nonalcoholic Fatty Liver Disease. Svegliati-Baroni G, et al. Gut. 2007 Mar 28 [Epub ahead of print].
Final results of a double-blind, placebo-controlled trial of the antifibrotic efficacy of interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or cirrhosis. Pockros PJ et al. Hepatology. 2007:Mar;45(3):569-78
Sustained virological response to interferon-alpha is associated with improved outcome in HCV-related cirrhosis: a retrospective study. Bruno S, et al. Hepatology. 2007 Mar;45(3):579-87
The Effect of Multiple Doses of Peginterferon alfa-2b on the Steady-State Pharmacokinetics of Methadone in Patients With Chronic Hepatitis C Undergoing Methadone Maintenance Therapy. Gupta SK, et al. J Clin Pharmacol. 2007 Mar 30; [Epub ahead of print]
The natural history of hepatitis C with severe hepatic fibrosis. Lawson A, et al. J Hepatol. 2007 Mar 7; [Epub ahead of print]
Does the clinical outcome of hepatitis C infection vary with the infecting hepatitis C virus type? Harris HE, et al. J Viral Hepat. 2007 Mar;14(3):213-20.
Effect of iron depletion on serum markers of fibrogenesis, oxidative stress and serum liver enzymes in chronic hepatitis C: results of a pilot study. Alexander J, et al. Liver Int. 2007 Mar;27(2):268-73.
Development of hepatocellular carcinoma in patients with chronic hepatitis C who had a sustained virological response to interferon therapy: a multicenter, retrospective cohort study of 1124 patients. Kobayashi S, et al. Liver Int. 2007 Mar;27(2):186-91.
basic and applied science, pre-clinical studies
CD4+ T Cell Responses in Patients with Chronic Hepatitis C Undergoing Peginterferon/Ribavirin Therapy Correlate with Faster, but Not Sustained, Viral Clearance. Aberle JH, et al. J Infect Dis. 2007 May 1;195(9):1315-9. Epub 2007 Mar 21.
GSTT1 and GSTM1 Null Genotypes May Facilitate Hepatitis C Virus Infection Becoming Chronic. Martinez C, et al. J Infect Dis. 2007 May 1;195(9):1320-3. Epub 2007 Mar 15.
Activation of the ER stress gene gadd153 by hepatitis C virus sensitizes cells to oxidant injury. Ciccaglione AR, et al. Virus Res. 2007 Mar 17; [Epub ahead of print]
Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells. Fillebeen C, et al. J Hepatol. 2007 Mar 2; [Epub ahead of print]
Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold. Aleshin AE, et al. Protein Sci. 2007 Mar 30; [Epub ahead of print]
Role of matrix metalloproteinases, proinflammatory cytokines, and oxidative stress-derived molecules in hepatitis C virus-associated mixed cryoglobulinemia vasculitis neuropathy. Saadoun D et al. Arthritis Rheum. 2007 Mar 28;56(4):1315-1324
Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection. Penna A, et al. Hepatology. 2007 Mar;45(3):588-601
Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity. Rollier CS, et al. Hepatology. 2007 Mar;45(3):602-13
Impact of aboriginal ethnicity on HCV core-induced IL-10 synthesis: interaction with IL-10 gene polymorphisms. Aborsangaya KB, et al. Hepatology. 2007 Mar;45(3):623-30
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Huang H, et al. Proc Natl Acad Sci U S A. 2007 Mar 21; [Epub ahead of print]
Impact of maternal HIV coinfection on the vertical transmission of hepatitis C virus: a meta-analysis. Polis CB, et al. Clin Infect Dis. 2007 Apr 15;44(8):1123-31. Epub 2007 Mar 7.
Liver-related mortality in human-immunodeficiency-virus-infected patients between 1995 and 2003 in the French GERMIVIC Joint Study Group Network (MORTAVIC 2003 Study). Rosenthal E, et al. J Viral Hepat. 2007 Mar;14(3):183-8.
Impact of Hepatitis C on HIV Progression in Adults With Alcohol Problems. Cheng DM, et al. Alcohol Clin Exp Res. 2007 Mar 31; [Epub ahead of print]
Hepatitis C virus infection is associated with insulin resistance among older adults with or at risk of HIV infection. Howard AA, et al. AIDS. 2007 Mar 12;21(5):633-41.
Hepatitis C virus (HCV) specific CD8+ cells produce TGF-beta that can suppress HCV-specific T cell responses. Alatrakchi N, et al. J Virol. 2007 Mar 21; [Epub ahead of print]
Rapid and early virological response to chronic Hepatitis C treatment with IFN alpha-2b or PEG- IFN alpha-2b plus ribavirin in HIV/HCV co-infected patients. Payan C, et al. Gut. 2007 Mar 22; [Epub ahead of print]
Cost-effectiveness of treatment for hepatitis C in an urban cohort co-infected with HIV. Campos NG, et al. Am J Med. 2007 Mar;120(3):272-9.
complimentary and alternative therapies
The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): a short review. Chaieb K, et al. Phytother Res. 2007 Mar 23; [Epub ahead of print]
Viusid, a nutritional supplement, in combination with interferon alpha-2b and ribavirin in patients with chronic hepatitis C. Vilar Gomez E, et al. Liver Int. 2007 Mar;27(2):247-59.
Reasons Why Patients Infected with Chronic Hepatitis C Virus Choose to Defer Treatment: Do They Alter Their Decision with Time? Khokhar OS, Lewis JH. Dig Dis Sci. 2007 Mar 15; [Epub ahead of print]
Multilevel modeling of intra-household spread of hepatitis C virus infection, Karachi, Pakistan. Akhtar S, Moatter T. Am J Trop Med Hyg. 2007 Mar;76(3):446-9.
The effects of HCV infection and management on health-related quality of life. Younossi Z, et al. Hepatology. 2007 Mar;45(3):806-16
Distributive syringe sharing among young adult injection drug users in five U.S. cities. Golub ET, et al. Drug Alcohol Depend. 2007 Mar 28; [Epub ahead of print]
Offers of Hepatitis C Care Do Not Lead to Treatment. Schackman BR, et al. J Urban Health. 2007 Mar 30; [Epub ahead of print]
Reconstruction of the Hepatitis C Virus Epidemic in the US Hemophilia Population, 1940-1990. Goedert JJ, et al. Am J Epidemiol. 2007 Mar 22; [Epub ahead of print]
Evaluation of a pharmacist-managed hepatitis C care clinic. Smith JP, et al. Am J Health Syst Pharm. 2007 Mar 15;64(6):632-6.
Assessment of FIBROSpect II to detect hepatic fibrosis in chronic hepatitis C patients. Zaman A, et al. Am J Med. 2007 Mar;120(3):280.e9-14.
Hepatitis C management by addiction medicine physicians: Results from a national survey. Litwin AH, et al. J Subst Abuse Treat. 2007 Mar 20; [Epub ahead of print]
Impact of pharmaceutical industry versus university sponsorship on survey response: A randomized trial among Canadian hepatitis C care providers. Myers RP, et al. Can J Gastroenterol. 2007 Mar;21(3):169-75.
A population-based prevalence study of hepatitis A, B and C virus using oral fluid in Flanders, Belgium. Quoilin S, et al. Eur J Epidemiol. 2007;22(3):195-202. Epub 2007 Mar 14.
Trends in Hepatitis B Virus, Hepatitis C Virus, and Human Immunodeficiency Virus Prevalence, Risk Behaviors, and Preventive Measures among Seattle Injection Drug Users Aged 18-30 Years, 1994-2004. Burt RD, et al. J Urban Health. 2007 Mar 14; [Epub ahead of print]
Variability of the area under the receiver operating characteristic curves in the diagnostic evaluation of liver fibrosis markers: impact of biopsy length and fragmentation. Poynard T, et a l. Aliment Pharmacol Ther. 2007 Mar 15;25(6):733-9.
Chronic illness experiences, clinical markers and living with hepatitis C. Sutton R, Treloar C. J Health Psychol. 2007 Mar;12(2):330-40.
C is the most common, chronic blood-borne