Caring Ambassadors Hepatitis C Program Newsletter
www.HepCChallenge.org
July 2009
Clinical Trials, Cohort Studies, Pilot Studies
Interferon induced
retinopathy and its risk in patients with diabetes and hypertension undergoing
treatment for chronic hepatitis C virus infection. D Panetta J, Gilani N. Aliment Pharmacol Ther. 2009 Jun
22. [Epub ahead of print]
Economic evaluation
of early monotherapy versus delayed monotherapy or combination therapy in
patients with acute hepatitis C in Germany. Dintsios
CM, Haverkamp A, Wiegand J, et al. Eur J Gastroenterol Hepatol. 2009 Jun 22. [Epub ahead of print]
Extended
treatment duration of peginterferon-alpha2b plus ribavirin for 72 and 96 weeks
in hepatitis C genotype 1-infected late responders. Nagaki M, Shimizu M, Sugihara JI, et al. Aliment
Pharmacol Ther. 2009 May 26. [Epub ahead of print]
A
randomised trial of pegylated-interferon-alpha-2a plus ribavirin with or
without amantadine in treatment-naïve or relapsing chronic hepatitis C
patients.
Langlet P, D'Heygere F, Henrion J, et al. Aliment
Pharmacol Ther. 2009 May 26. [Epub ahead of print]
Decline in male
sexual desire, function, and satisfaction during and after antiviral therapy
for chronic hepatitis C. Dove LM, Rosen RC, Ramcharran
D, Wahed AS, Belle SH, Brown RS, Hoofnagle JH; Virahep-C Study Group. Gastroenterology. 2009 Jun 12.
[Epub ahead of print]
Efficacy of
peginterferon-alpha-2b plus ribavirin in patients aged 65 years and older with
chronic hepatitis C.Honda T, Katano Y, Shimizu J, et al. Liver Int. 2009
Jun 12. [Epub ahead of print]
Impact of ribavirin
plasma level on sustained virological response in patients treated with
pegylated interferon and ribavirin for chronic hepatitis C. Breilh D, Foucher J, Castéra L, et al. Aliment Pharmacol Ther. 2009 Jun 11. [Epub ahead of print]
Factors associated
with the progression of hepatic fibrosis in end-stage kidney disease patients
with hepatitis C virus infection. Becker VR,
Badiani RG, Lemos LB, et al. Eur J Gastroenterol Hepatol. 2009
Jun 11. [Epub ahead of print]
Development
of hepatocellular carcinoma in elderly patients with chronic hepatitis C with
or without elevated aspartate and alanine aminotransferase levels. Kobayashi M, Suzuki F, Akuta N, et al. J Gastroenterol. 2009 Jun 11:1-9. [Epub ahead of print]
Response
to hepatitis A and B vaccine alone or in combination in patients with chronic
hepatitis C virus and advanced fibrosis. Kramer ES, Hofmann C, Smith PG, Shiffman ML,
Sterling RK. Dig Dis Sci. 2009 Jun 11. [Epub ahead of print]
Hepatitis C virus infection and the risk of
coronary disease. Butt AA, Xiaoqiang
W, Budoff M, Leaf D, Kuller LH, Justice AC. Clin Infect Dis. 2009 Jul
15;49(2):225-32
Light and moderate alcohol consumption significantly reduces
the prevalence of fatty liver in the Japanese male population. Gunji T, Matsuhashi
N, Sato H, et al. Am J Gastroenterol. 2009 Jun 23.
[Epub ahead of print]
Quality of life, depression, and cytokine patterns in
patients with chronic hepatitis C treated with antiviral therapy. Falasca K, Mancino
P, Ucciferri C, et al. Clin Invest Med. 2009 Jun 1;32(3):E212-8.
Basic and Applied Science, Pre-Clinical Studies
Predictive values
of amino acid sequences of the core and NS5A regions in antiviral therapy for
hepatitis C: a Japanese multi-center study. Okanoue T,
Itoh Y, Hashimoto H, et al J Gastroenterol. 2009 Jun 11.
[Epub ahead of print]
Differences
in viral kinetics between genotypes 1 and 2 of hepatitis C virus after single
administration of standard interferon-alpha. Toyoda H, Kumada
T, Kiriyama S, et al. J Med Virol. 2009 Jun 23;81(8):1354-1362.
[Epub ahead of print]
Hepatitis C virus core, NS3, NS4B and NS5A are the
major immunogenic proteins in humoral immunity in chronic HCV infection. Sillanpaa M, Melen
K, Porkka P, et al. Virol J. 2009 Jun 23;6(1):84.
[Epub ahead of print]
Enhancement of the expression of HCV core gene does not
enhance core-specific immune response in DNA immunization: advantages of the
heterologous DNA prime, protein boost immunization regiment. Alekseeva E,
Sominskaya I, Skrastina D, et al. Genet Vaccines Ther. 2009 Jun 8;7(1):7. [Epub ahead of print]
Tight junction-associated protein occludin is required
for a post-binding step in hepatitis C virus entry and infection. Benedicto
I, Molina-Jiménez F, Bartosch B, et al. J Virol. 2009
Jun 10. [Epub ahead of print]
Presence of HCV-RNA after ultracentrifugation of serum
samples during the follow-up of chronic hepatitis C patients with a sustained
virological response may predict reactivation of hepatitis C virus infection. Castillo I,
Bartolomé J, Quiroga JA, Barril G, Carreño V. Aliment Pharmacol Ther. 2009 Jun 11. [Epub ahead of print]
HIV/HCV Coinfection
Long-term
serologic follow-up of isolated hepatitis B core antibody in HIV-infected and
HIV-uninfected women. French AL, Lin
MY, Evans CT, et al. Clin Infect Dis. 2009 Jul 1;49(1):148-54.
Hepatitis C virus
infections among HIV-infected men who have sex with men: an expanding epidemic.
Urbanus AT, van de Laar TJ, Stolte IG, et al. AIDS. 2009 Jun 17. [Epub ahead of print]
Liver
stiffness as a predictor of esophageal varices requiring therapy in
HIV/hepatitis C virus-coinfected patients with cirrhosis. Pineda JA, Recio E, Camacho A, et al. J Acquir Immune Defic Syndr. 2009
May 28. [Epub ahead of print]
Human
immunodeficiency virus and hepatitis C infections induce distinct immunologic
imprints in peripheral mononuclear cells. Kottilil
S, Yan MY, Reitano KN,et al. Hepatology. 2009 May 6;50(1):34-45. [Epub ahead of print]
Peginterferon
plus ribavirin for chronic hepatitis C in patients with human immune-deficiency
virus.
Gluud LL, Marchesini E, Iorio A. Am J Gastroenterol.
2009 Jun 9. [Epub ahead of print]
Complementary & Alternative Medicine
Effect of coffee
and green tea consumption on the risk of liver cancer: cohort analysis by
hepatitis virus infection status. Inoue M,
Kurahashi N, Iwasaki M, et al. Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1746-53.
Proanthocyanidin
from blueberry leaves suppresses expression of subgenomic hepatitis C Virus
RNA. Takeshita M, Ishida YI, Akamatsu E, et al. J Biol
Chem. 2009 Jun 16. [Epub ahead of print]
Epidemiology, Diagnostics, and Miscellaneous Works
Liver biopsies for
chronic hepatitis C: Should nonultrasound-guided biopsies be abandoned? Flemming JA, Hurlbut DJ, Mussari B, Hookey LC. Can J Gastroenterol. 2009
Jun;23(6):425-30.
Validation of hepascore, compared with simple indices
of fibrosis, in patients with chronic hepatitis C virus infection in United
States. Becker
L, Salameh W, Sferruzza A, et al.
Zhang
K, ng Chen R, Malik R, Reitz R, Nasser I, Afdhal NH. Clin Gastroenterol
Hepatol. 2009 Jun;7(6):696-701.
Healthcare-associated hepatitis C virus
transmission among patients in an abdominal organ transplant center. Thompson ND, Hellinger WC, Kay RS, et al. Transpl
Infect Dis. 2009 May 26. [Epub ahead of print]
Increasing public awareness about hepatitis C:
development and validation of the brief hepatitis C knowledge scale. Balfour L, Kowal J, Corace KM, Tasca GA,
Krysanski V, Cooper CL, Garber G. Scand J Caring Sci. 2009 Jun 5. [Epub ahead
of print]
Hepatitis C performance measure on hepatitis A and B
vaccination: Missed opportunities? Hernandez B, Hasson NK, Cheung R. Am J
Gastroenterol. 2009 Jun 2. [Epub ahead of print]
Chronic liver disease mortality among male
prison inmates in Texas, 1989-2003. Harzke
AJ, Baillargeon J, Paar DP, Pulvino J, Murray OJ. Am
J Gastroenterol. 2009 Jun;104(6):1412-9. Epub
2009 Apr 21.
Improving access to care by allowing
self-referral to a hepatitis C clinic. Doucette
KE, Robson V, Shafran S, Kunimoto D. Can J Gastroenterol. 2009 Jun;23(6):421-4.
Prevalence of problem alcohol use among
patients attending primary care for methadone treatment. Ryder N, Cullen W, Barry J, Bury G, Keenan E, Smyth BP.
BMC Fam Pract. 2009 Jun 11;10(1):42.
[Epub ahead of print]
Prevalence and trends of human
immunodeficiency virus, hepatitis B virus, and hepatitis C virus among blood
donors in Iran, 2004 through 2007. Amini Kafi-Abad S,
Rezvan H, Abolghasemi H, Talebian A. Transfusion. 2009 Jun
10. [Epub ahead of print]
Effective use of
FibroTest to generate decision trees in hepatitis C. Lau-Corona D, Pineda LA, Avilés HH, et al World J Gastroenterol. 2009 Jun
7;15(21):2617-22.
Prevalence of human
cytomegalovirus co-infection in patients with chronic viral hepatitis B and C:
A comparison of clinical and histological aspects. Bayram A, Ozkur A, Erkilic S. J Clin Virol. 2009 Jun 2.
[Epub ahead of print]